Vacant postdoctoral position to study the DNA damage response in reproductive aging using mouse models – University of Copenhagen

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05 February 2018

Vacant postdoctoral position to study the DNA damage response in reproductive aging using mouse models

Center for Chromosome Stability, Department of Cellular and Molecular Medicine at the University of Copenhagen is looking for a postdoctoral scientist to join the Center, starting in March 2018, or upon agreement.

The position is available in the laboratory of Prof. ER Hoffmann lab and is financed by an ERC Consolidator Award. The CCS opened in 2015 and is financed for six years by the DNRF. The position is available in the first instance for 3 years, with a possible extension for two further years.  
 
Job description 
Hoffmann lab is recruiting a talented and motivated postdoctoral scientist with a background in mouse genetics. The scientist will be involved in the maintenance and implementation of assessing ovarian function and other aging phenotypes in mouse models of DNA repair and DNA damage response (DDR) genes. The DDR was recently implicated in determining reproductive lifespan in human and the successful candidate will be involved in model selection based on genome-wide association studies (GWAS) and RNA expression profiles from oocytes and preimplantation embryos. The project will involve human cell line work to phenotype common variants in human DDR genes in response to DNA damaging agents. Initially, the project will focus on the role of ATR-CHK1 and ATM-CHK2-BRCA1 but other models are also available locally in the Center for Healthy Aging and the CCS. 
 
Application deadline: 28-02-2018
 
Read more about the vacant postdoc position