Publications 2015 – University of Copenhagen

Publications 2015

  • Kliszczak M, Sedlackova H, Pitchai GP, Streicher WW, Krejci L, Hickson ID. Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells. Oncotarget 6. 2015 Nov 17, 40464-40479

  • Thorslund T, Ripplinger A, Hoffmann S, Wild T, Uckelmann M, Villumsen B, Narita T, Sixma TK, Choudhary C, Bekker-Jensen S, Mailand N. Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.  Nature. 2015 Nov 19;527(7578):389-93

  • Newman JA, Savitsky P, Allerston CK, Bizard AH, Özer Ö, Sarlós K, Liu Y, Pardon E, Steyaert J, Hickson ID, Gileadi O. Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes.
    Nucleic Acids Res. 2015 Apr 21. pii: gkv373.

  • Lopez-Contreras AJ*, Specks J, Barlow JH, Ambrogio C, Desler C, Vikingsson S, Rodrigo-Perez S, Green H, Rasmussen LJ, Murga M, Nussenzweig A, Fernandez-Capetillo O*.  Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice . Genes and Development 29, 2015 Apr 1. 690-695    *Co-corresponding authors 

  • Bursomanno S, McGouran JF, Kessler BM, Hickson ID, Liu Y. Regulation of SUMO2 Target Proteins by the Proteasome in Human Cells Exposed to Replication Stress.  Journal of Proteome Research 14, 1687-1699.

  • Chu, W.K., Payne, M.J., Beli, P., Hanada, K., Choudhary, C. and Hickson, I.D. (2015) FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51. Nature Communications 6, 5931

  • Xing, M., Wang, X., Palmai-Pallag, T., Shen H., Helleday, T., Hickson, I.D. and Ying, S. (2015) Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response. Oncotarget 6, 37638-37646.

  • Minocherhomji, S., Ying, S., Bjerregaard, V.A., Bursomanno, S., Aleliunaite, A., Wu, W., Mankouri, H.W., Shen, H., Liu, Y. and Hickson, I.D. (2015) Replication stress activates DNA repair synthesis in mitosis. Nature 528, 286-290.

  • Nielsen, C.F., Huttner, D., Bizard, A.H., Hirano, S., Li, T-N., Palmai-Pallag, T., Bjerregaard, V.A., Liu, Y., Nigg, E.A., Wang, L.H-C. and Hickson, I.D. (2015) PICH promotes sister chromatid disjunction in mitosis: evidence of functional co-operation with topoisomerase II. Nature Communications 6, 8962.

  • Specks, J., Lecona, E., Lopez-Contreras, AJ. and Fernandez-Capetillo, O. (2015) A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development. Molecular and Cellular Biology 35, 2910-2917.

  • Lecona, E., Rodriguez-Acebes, S., Specks, J., Lopez-Contreras, A.J., Ruppen, I., Murga, M., Muñoz, J., Mendez, J. and Fernandez-Capetillo, O. (2016) USP7 is a SUMO deubiquitinase essential for DNA replication. Nature Structural & Molecular Biology