New publication in Nature Communications from the Liu group

Mitotic DNA synthesis (MiDAS) was proposed to utilize break-induced DNA replication, a form of homology-directed DNA repair (HDR). Here, the researchers in CCS found that core DNA end-resection factors required for HDR, including MRE11, CtIP and BRCA1, and a RecQ family helicase, WRN, are essential for MiDAS.

See the original publication at:
DNA double-strand break end resection factors and WRN facilitate mitotic DNA synthesis in human cells. 
Barwacz SA, Lundgaard K, Wu W, Richter PH, Ren L, Bhowmick R, Gonçalves Dinis MM, Kanemaki MT,  Liu Y.
Nature Communications. 2025 Aug 25;16(1):7901.

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